More than just glue

PDZ domains: More than just a glue.

P domains are part of a molecular scaffold that holds multiprotein signaling complexes together. It is generally believed that the role of PDZ domains is to position target ion channels, receptors, or other signaling molecules in correct spatial arrangement in relation to each other and to specialized regions of the cell (1–4). Two recent reports, one published in Cell (5) and another in this i...

More than just vanilla.

More than just big ears

To the non-specialist, large ears in elephants used to mean African, small ears, Indian. But to taxonomists African elephants have long posed a more complex puzzle. During the nineteenth century, it was fashionable for wealthy trophy hunters to assign their own names to species they had shot destined for the museums of Europe. At least 18 elephant subspecies were claimed following this fashion....

EHPnet: More Than Just Unleaded

Periostin: more than just an adhesion molecule.

The form and function of the heart is determined by the dynamic interaction of both intra and extracellular signals. During normal growth of the neonatal heart myocytes undergo hypertrophy in response to variety of signals including changes in blood pressure1–3. The number of fibroblasts also increase and the collagenous connective tissue is formed.4,7,8 The coordination of these postnatal sign...